SLC17A5, solute carrier family 17 member 5, 26503

N. diseases: 252; N. variants: 47
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 Biomarker disease BEFREE Difference analyses, odds ratio calculation, logistic and predictive analyses were used to evaluate the association and discrimination ability between AIP, BMI, waist, SBP, DBP, BG, ALT, AST and FL. 31511022 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 Biomarker disease BEFREE The Hepatic Steatosis Index (HSI) and the Fatty Liver Index (FLI) were estimated using Body Mass Index (BMI), waist circumference, and fasting concentrations of glucose, triglycerides, and hepatic enzymes (ALT, AST, GGT). 30823422 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 AlteredExpression disease BEFREE The alcohol exposure increased the levels of ALT, AST, TNF-α and IL-6 inflammatory factors and liver steatosis. 31429848 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 Biomarker disease BEFREE Multivariate logistic regression models, adjusted for age, gender, BMI, sampling season, glucose, total cholesterol, triglycerides, HOMA-IR, hs-CRP, ALT, AST, and elevated VAT, revealed an association between FL and vitamin D (VD) insufficiency (RM 1.61 [0.99-2.61]) and with VDD (RM 1.68 [1.02-2.77]); however, statistical significance was lost when including caloric consumption and physical activity in the model. 29735791 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 Biomarker disease BEFREE The outcome measures were body mass index (BMI), blood lipids, fasting blood sugar (FBS), liver enzymes (ALT and AST), and ultrasonographic measurements of liver steatosis and shear wave elastography (SWE). 31375753 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 GeneticVariation disease BEFREE Correlations are analyzed among petroleum and liver cirrhosis mortality, fatty liver, alanine amino transferase (abbreviated as ALT), aspartate amino transferase (abbreviated as AST). 30296610 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 Biomarker disease BEFREE CML was not correlated with liver steatosis (r=0.07, P=0.683), but was positively correlated with AST (r=0.34, P=0.04), GGT (r=0.38, P=0.023) and HbA1C (r=0.37, P=0.027). sRAGE tended to be higher in subjects with NFS<-1.455 compared with NFS>-1.455 (1287±450 n=36 vs. 1051±364 n=13, P=0.08). 28179090 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 AlteredExpression disease BEFREE We demonstrated that ten-day alcohol feeding primed the liver to LPS-induced lipid accumulation and liver injury with significantly increased hepatic steatosis and serum AST level as well as hepatic cellular NF-κB activation. 28839246 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 AlteredExpression disease BEFREE Moreover, the increased plasmatic levels of AST (aspartate aminotransferase), ALT (alanine aminotransferase) and AP (alkaline phosphatase), as well as liver histology suggest stress-induced liver steatosis. 28448552 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.100 GeneticVariation disease BEFREE Variables associated with the steatosis group were: higher serum levels of AST (P<0.04), alanine aminotransferase (P<0.02), gamma-GT (P<0.004), genotype 3a (P<0.03) and severity of histology (staging P<0.05) but at multiple linear regression analysis only genotype 3a and staging were significantly associated with LS. 17032413 2006