|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
L1 comparing to L0 presented higher fasting triglycerides (p=0.004), insulin (p=0.002), INS/GLU (p=0.003), HOMA-IR (p=0.002), GGTP (p=0.006), AST/SGOT (p=0.002), postprandial glucose (p=0.001) and insulin (p=0.011).
|
31071683 |
2019 |
|
Liver diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
<b>Objectives:</b> To validate the usefulness of a hepatic fibrosis scoring system fibrosis-4 (FIB-4) index to diagnose liver diseases in rheumatoid arthritis (RA) patients treated with methotrexate (MTX).<b>Methods:</b> The FIB-4 index (age(years) × AST(U/L)/platelet (PLT) (10<sup>9</sup>/L) × √ALT(U/L)), proposed as a predictor for liver fibrosis in HIV/HCV coinfection, was evaluated in this study.
|
30379089 |
2019 |
|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
LincRNA-p21 level was negatively correlated with HBV DNA (P = 0.02), ALT (P = 0.01) and AST (P = 0.01) in patients with liver disease, but not correlated with gender (P = 0.24), age (P = 0.11) and AFP level (P = 0.84).
|
30704781 |
2019 |
|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Liver disease was defined as elevated ALT or AST.
|
28809726 |
2018 |
|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Although AST and GGT are substantially increased by liver disease, they can give useful information on recent alcohol intake in patients with alcoholic cirrhosis when appropriate cut-off limits are used.
|
29277282 |
2018 |
|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Elevated AST and GGT may be markers for risk of advanced liver disease.
|
27555301 |
2017 |
|
Liver diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Liver disease was defined as an elevation of any of the following parameters: alanine or aspartate aminotransferase (ALT and AST), total bilirubin, and gamma glutamyl transferase (GGTP).
|
28951598 |
2017 |
|
Liver diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Also, to explicate a possible role of SEN virus in liver disease and established changes in blood factors, the serum aminotransferases (ALT and AST) and some of the blood factors were measured.
|
20044930 |
2010 |
|
Liver diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
No association was found between the serum AST (aspartate aminotransferase), activity grade, or stage of liver disease and the presence of occult hepatitis B. Serum ALT levels were slightly higher in patients without occult hepatitis B (46 vs. 35 IU/L), and the median years since first injection drug use was somewhat longer in those without occult hepatitis B (24 vs. 20 years).
|
14752822 |
2004 |
|
Liver diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, no correlation was observed between serum HCV RNA levels and the severity of liver disease as judged by the values of serum albumin (r = 0.175), bilirubin (r = 0.217), ALT (r = 0.06) and AST (r = 0.004) levels.
|
15285030 |
2004 |
|
Liver diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In conclusion, regulation of AST isozymes during liver disease is complex, including differential, pretranslational and translational or posttranslational mechanisms.
|
1916663 |
1991 |