|
Graves Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Of all GD, 12% (95% CI 2-42%) likely had spontaneous remission, 56% (95% CI 34-76%) required only antithyroid drugs, 22% (95% CI 13-32%) needed additional RAI, and 11% (95% CI 0.9-29%) underwent definitive surgery.
|
31452116 |
2020 |
|
Myocardial Ischemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
For example, an increment in the two-day average (lag1-2) level of PM<sub>2.5</sub> by one IQR (34.4 µg/m<sup>3</sup>) was associated with a 6.3% (95%CI: 3.0%-9.8%) increase in the daily count of admissions for ischemic heart disease in Hanoi and with 23.2% (95%CI: 11.1%-36.5%) for cardiac failure in Quang Ninh.
|
31731158 |
2020 |
|
Dyssomnias
|
0.010 |
Biomarker
|
disease |
BEFREE |
The term sleep problem (total and female; lag -1) consistently showed significant negative correlations.
|
31733460 |
2020 |
|
Sleep Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
The term sleep problem (total and female; lag -1) consistently showed significant negative correlations.
|
31733460 |
2020 |
|
Hand, Foot and Mouth Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
During cold season, we observed significant associations between SO<sub>2</sub> and HFMD among all subgroups except for children aged 5-14 years old and the adverse effects occurred on lag0, lag1, lag01, lag02.
|
30577010 |
2019 |
|
Secondary malignant neoplasm of bone
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Abbreviations: BM</b> = bone metastases; <b>COX</b> = multivariate analyses; <b>DM</b> = distant metastases; <b>DSM</b> = disease-specific mortality; <b>DSS</b> = disease-specific survival; <b>DTC</b> = differentiated thyroid carcinoma; <b>ETE</b> = extrathyroidal extension; <b>LNM</b> = lymph node metastases; <b>OM</b> = overall mortality; <b>OS</b> = overall survival; <b>PTCFV</b> = papillary thyroid carcinoma; <b>RAI</b> = radioactive iodine; <b>SM</b> = spinal metastases; <b>SRE</b> = skeletal-related event; <b>txWBS</b> = whole-body scan after RAI therapy.
|
30657361 |
2019 |
|
Neurotic, stress-related and somatoform disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
The ARR (95% CI) in the model adjusted for O<sub>3</sub> was 1.015 (1.003-1.029) by 10 μg/m<sup>3</sup> of PM<sub>2.5</sub> on Lag 1 for F40-F49 (Neurotic, stress-related and somatoform disorders).
|
30522934 |
2019 |
|
SVEINSSON CHORIORETINAL ATROPHY
|
0.010 |
Biomarker
|
disease |
BEFREE |
TG, BRCA1, and NSMCE2 haplotypes were identified as being uniquely associated with RAI-R AA patients of >80% African ancestry.
|
30654714 |
2019 |
|
Cerebral Infarction
|
0.010 |
Biomarker
|
disease |
BEFREE |
RAI belongs to the Shc family proteins, it is mainly neuron specific and protects against cerebral ischemia.
|
29057481 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
Biomarker
|
disease |
BEFREE |
A1C = glycated hemoglobin A1c; BMI = body mass index; CI = confidence interval; DCSI = Diabetes Complications Severity Index; DPP-4 = dipeptidyl peptidase-4; EHR = electronic health record; GLP-1 RA = glucagon-like peptide-1 receptor agonist; ICD-9-CM = International Classification of Diseases-Ninth Revision-Clinical Modification; ICD-10-CM = International Classification of Diseases-Tenth Revision-Clinical Modification; OAD = oral antidiabetes drug; OR = odds ratio; RAI = rapid-acting insulin; SGLT-2 = sodium-glucose cotransporter-2; T2D = type 2 diabetes.
|
29975575 |
2018 |
|
Fatty Liver
|
0.010 |
Biomarker
|
disease |
BEFREE |
We found LASS2<sup>-/-</sup> mice were resistant to HFD-induced hepatic steatosis and insulin resistance.
|
29626628 |
2018 |
|
Malaria
|
0.010 |
Biomarker
|
disease |
BEFREE |
The model showed that humidity (lag 2), precipitation (lag 3), precipitation (lag 12), migration (lag1) and previous malaria cases (lag 12) had a significant relationship with malaria cases.
|
29900134 |
2018 |
|
Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, using SKNMC cells stably expressing RAI, we defined a role of RAI in NB cell responses to hypoxia.
|
29057481 |
2018 |
|
Strabismus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Statin users on average had 15 mm of total strabismus surgery compared with 21.4 mm in the nonuser group (P = 0.09) and had fewer muscles involved radiographically (4.3 vs 5.1 [P = 0.08]) CONCLUSIONS: Compared to nonusers, statin users tended to have fewer decompressions, less restriction, fewer surgeries, and fewer muscles involved despite having more current smokers (36% vs 5%), more males, more RAI, and fewer thyroidectomies, all of which are associated with worse TED.
|
30075294 |
2018 |
|
Thyroid associated opthalmopathies
|
0.010 |
Biomarker
|
disease |
BEFREE |
Statin users on average had 15 mm of total strabismus surgery compared with 21.4 mm in the nonuser group (P = 0.09) and had fewer muscles involved radiographically (4.3 vs 5.1 [P = 0.08]) CONCLUSIONS: Compared to nonusers, statin users tended to have fewer decompressions, less restriction, fewer surgeries, and fewer muscles involved despite having more current smokers (36% vs 5%), more males, more RAI, and fewer thyroidectomies, all of which are associated with worse TED.
|
30075294 |
2018 |
|
Central neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, using SKNMC cells stably expressing RAI, we defined a role of RAI in NB cell responses to hypoxia.
|
29057481 |
2018 |
|
Papillary Thyroid Microcarcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A total of 52 patients with unifocal mPTC, NI-EFV from five tertiary hospitals who had at least one year clinical follow-up (FU) without post-operative RAI administration were included in the study.
|
29204912 |
2018 |
|
PNEUMOTHORAX, PRIMARY SPONTANEOUS
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Among air pollutant concentrations, O<sub>3</sub> in lag-1 (p = 0.017) and lag-2 (p = 0.038), NO<sub>2</sub> in lag-1 (p = 0.015) and lag-2 (p = 0.009), PM<sub>10</sub> in lag-1 (p = 0.012), and PM<sub>2.5</sub> in lag-1 (p = 0.021) and lag-2 (p = 0.032) were significantly different between no PSP and PSP days.
|
29685359 |
2018 |
|
Steatohepatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
We found LASS2<sup>-/-</sup> mice were resistant to HFD-induced hepatic steatosis and insulin resistance.
|
29626628 |
2018 |
|
Childhood Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, using SKNMC cells stably expressing RAI, we defined a role of RAI in NB cell responses to hypoxia.
|
29057481 |
2018 |
|
Miscarriage
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Pregnancy (RAI group 62%; control group 61%) and miscarriage rates (18% and 26%) were similar.
|
29302874 |
2018 |
|
Refractory Thyroid Gland Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Two multi-kinase inhibitors (sorafenib and lenvatinib) are now FDA approved for treatment of RAI refractory thyroid cancer and now play an important role in the management of progressive, metastatic and surgically incurable disease.
|
28687430 |
2018 |
|
Chylothorax
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, the chylothorax did not decrease with conservative therapy.Therefore, RAI was administered.
|
28835765 |
2017 |
|
Dengue Fever
|
0.010 |
Biomarker
|
disease |
BEFREE |
Based on the dengue-2 model, variables with the highest odds ratio were AT-lag1 and RH-lag0 indicating an 8.9 and 18.1 times greater probability of a moderate MID, respectively.
|
28700047 |
2017 |
|
nervous system disorder
|
0.010 |
Biomarker
|
group |
BEFREE |
Genes relevant to neuronal function or neurological disease include up-regulated genes: PKC-alpha (<i>Prkca</i>), MECP2 (<i>Mecp2</i>), STRN4 (<i>Strn4</i>), SLC40a1 (<i>Slc40a1</i>), POLD2 (<i>Pold2</i>), PCSK2 (<i>Pcsk2</i>), and down-regulated genes: KRT12 (<i>Krt12</i>), LASS1 (<i>Cers1</i>), PLAT (<i>Plat</i>), and NRXN1 (<i>Nrxn1</i>).
|
28367114 |
2017 |