FOXD3, forkhead box D3, 27022

N. diseases: 78; N. variants: 4
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE The transcription factors PAX3 and FOXD3 have essential roles in melanoblasts and melanoma. 26252164 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Here, we discover a molecular pathway wherein PAX3 and FOXD3 promote CXCR4 gene expression in melanoma. 26205821 2015
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE FOXD3 is downregulated during the migration of the melanocyte lineage from the neural crest, and our previous work supports a role for FOXD3 in suppressing melanoma cell migration and invasion. 25061102 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Ectopic FOXD3 expression potently inhibited melanoma cell growth without altering mutant B-RAF activation of ERK1/2. 20332228 2010