|
Schizophrenia
|
0.330 |
Biomarker
|
disease |
BEFREE |
Ten genes of importance for HNK-1 biosynthesis (B3GAT1, B3GAT2, and CHST10) or for the formation of perineuronal nets (TNR, BCAN, NCAN, HAPLN1, HAPLN2, HAPLN3, and HAPLN4) were investigated for potential involvement in schizophrenia (SCZ) susceptibility, by genotyping 104 tagSNPs in the Scandinavian Collaboration on Psychiatric Etiology sample (849 cases; 1602 control subjects).
|
20950796 |
2011 |
|
Schizophrenia
|
0.330 |
Biomarker
|
disease |
PSYGENET |
Ten genes of importance for HNK-1 biosynthesis (B3GAT1, B3GAT2, and CHST10) or for the formation of perineuronal nets (TNR, BCAN, NCAN, HAPLN1, HAPLN2, HAPLN3, and HAPLN4) were investigated for potential involvement in schizophrenia (SCZ) susceptibility, by genotyping 104 tagSNPs in the Scandinavian Collaboration on Psychiatric Etiology sample (849 cases; 1602 control subjects).
|
20950796 |
2011 |
|
Schizophrenia
|
0.330 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophrenia.
|
16815618 |
2006 |
|
Schizophrenia
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
This leads us to the hypothesis that polymorphic or other variation of the 11q telomere may affect the activity of B3GAT1 and be a risk factor for schizophrenia and related psychoses in the general population.
|
12874601 |
2003 |
|
Schizophrenia
|
0.330 |
GeneticVariation
|
disease |
LHGDN |
This leads us to the hypothesis that polymorphic or other variation of the 11q telomere may affect the activity of B3GAT1 and be a risk factor for schizophrenia and related psychoses in the general population.
|
12874601 |
2003 |
|
Prostate cancer, familial
|
0.300 |
Biomarker
|
disease |
CTD_human |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
|
PROSTATE CANCER, HEREDITARY, 1
|
0.300 |
Biomarker
|
disease |
CTD_human |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
|
Non-alcoholic Fatty Liver Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
|
24211274 |
2014 |
|
Nonalcoholic Steatohepatitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
|
24211274 |
2014 |
|
Pulmonary Fibrosis
|
0.200 |
Biomarker
|
disease |
RGD |
Glycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-β1-induced pulmonary fibrosis.
|
24127863 |
2014 |
|
Prostate carcinoma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
In addition to reviewing these cases, we reviewed the relevant literature pertaining to this form of cancer and assessed the immunohistochemical staining for CD57 on the available tumor samples.
|
31369187 |
2019 |
|
Cytomegalovirus Infections
|
0.090 |
AlteredExpression
|
group |
BEFREE |
To our knowledge, our findings provide new insights into the roles of KLRG1 and CD57 expression in human T cells, forming the basis for a refined model of CD8<sup>+</sup> T cell differentiation during CMV infection.
|
31554693 |
2019 |
|
Cytomegalovirus Infections
|
0.090 |
Biomarker
|
group |
BEFREE |
A population of Natural Killer (NK) cells expressing the activating receptor NKG2C and the maturation marker CD57 expands in response to human cytomegalovirus (HCMV) infection.
|
31211698 |
2019 |
|
Cytomegalovirus Infections
|
0.090 |
AlteredExpression
|
group |
BEFREE |
Whereas, FcRγ<sup>neg</sup> NK cells in CMV infection are reported to express increased levels of the maturation marker CD57, the FcRγ<sup>neg</sup> NK cells observed in our CMV-negative vaccine cohort express less CD57 than their FcRγ<sup>+</sup> counterparts.
|
31824507 |
2019 |
|
Neoplasms
|
0.090 |
AlteredExpression
|
group |
BEFREE |
Remarkably, upon 5 days in the developing neural tube, iHDAC-treated GBM cells ectopically expressed HNK-1, a tumor-suppressor marker tightly correlated to increased survivor of patients.
|
31531023 |
2019 |
|
Neoplasms
|
0.090 |
AlteredExpression
|
group |
BEFREE |
At baseline, NK cells in the tumor lymph node had a naïve phenotype albeit they were more differentiated than NK cells derived from control tonsils as determined by the frequency of CD56<sup>dim</sup> NK cells and the expression of killer cell immunoglobulin-like receptors (KIR), CD57 and CD16.
|
31572357 |
2019 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
The increase of CD8+CD57+ T cells in the peripheral blood of patients with cancer has been associated with prognosis, which suggests their suitability as a candidate immunological marker.
|
29928332 |
2018 |
|
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Neurokinin1 (NK1) receptor has played a vital role in the development of tumor.
|
29843798 |
2018 |
|
Cytomegalovirus Infections
|
0.090 |
Biomarker
|
group |
BEFREE |
We extend previous observations of the impact of CMV on CD8<sup>+</sup> T cell functionality to the CD4<sup>+</sup> T cell compartment, revealing CD57 as a polyfunctionality marker of T cells which expands after CMV infection.
|
27566833 |
2017 |
|
Cytomegalovirus Infections
|
0.090 |
AlteredExpression
|
group |
BEFREE |
With a mediation analysis we demonstrated that cytomegalovirus (CMV) infection, which is an important driving force of immunosenescence, largely accounted for elevated CD57 expression observed in ELA.
|
29089944 |
2017 |
|
Cytomegalovirus Infections
|
0.090 |
AlteredExpression
|
group |
BEFREE |
As chronic cytomegalovirus (CMV) infection is probably one of the major driving forces of immunosenescence, and its persistent infection results in functional and phenotypic changes to the T-cell repertoire, the aim of this study was to analyze the effect of CMV-seropositivity and aging on the expression of CD300a and CD161 inhibitory receptors, along with the expression of CD57 marker on CD4<sup>+</sup>, CD8<sup>+</sup>, CD8<sup>+</sup>CD56<sup>+</sup> (NKT-Like) and CD4<sup>-</sup>CD8<sup>-</sup> (DN) T-cell subsets.
|
28626460 |
2017 |
|
Cytomegalovirus Infections
|
0.090 |
Biomarker
|
group |
BEFREE |
We here studied whether subclinical CD is associated with changes in blood CD57-expressing and Vδ1-expressing lymphocytes in children, and whether cytomegalovirus (CMV) infection modifies this association.
|
28456719 |
2017 |
|
Neoplasms
|
0.090 |
AlteredExpression
|
group |
BEFREE |
Tumor stroma CD57 and CD8 expression was associated with lymphnode status and independently predicts survival of OSCC patients.
|
28549420 |
2017 |
|
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Here, we report two rare cases of schwannoma-like tumor in the anterior cranial fossa that showed negative staining for Leu7, but positive staining for Schwann/2E, and discuss their origin.
|
27925298 |
2017 |