Anemia, Hemolytic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Anemia, Hemolytic, Acquired
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Anemia, Microangiopathic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Hepatitis, Toxic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Respiratory Distress Syndrome, Adult
|
0.300 |
Biomarker
|
disease |
CTD_human |
MicroRNA and mRNA expression profiling in rat acute respiratory distress syndrome.
|
25070658 |
2014 |
Adenocarcinoma of lung (disorder)
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Microangiopathic hemolytic anemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Non-alcoholic Fatty Liver Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.
|
29289645 |
2018 |
Hepatitis, Drug-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Nonalcoholic Steatohepatitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.
|
29289645 |
2018 |
Drug-Induced Acute Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Chemical and Drug Induced Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Chemically-Induced Liver Toxicity
|
0.300 |
Biomarker
|
disease |
CTD_human |
Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress.
|
25411909 |
2015 |
Myocardial Infarction
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.
|
21211798 |
2011 |
Psoriasis
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Expression studies using Affymetrix arrays suggested that the HCR risk allele has specific functional consequences relevant to the pathogenesis of psoriasis.
|
15190014 |
2004 |
Psoriasis
|
0.090 |
Biomarker
|
disease |
BEFREE |
With two rounds of the method and five single nucleotide polymorphisms, molecular haplotypes of 29.3 kb spanning the HCR and CDSN genes, two genes associated with the susceptibility of psoriasis, of 11 members, belonging to a CEPH family, were revealed.
|
16134125 |
2005 |
Psoriasis
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
These results provide strong evidence for the HCR*WWCC allele as a major genetic determinant for psoriasis, probably by a mechanism impacting on keratinocyte proliferation.
|
11875053 |
2002 |
Psoriasis
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Aberrant function of the CCHCR1 gene (Coiled-Coil alpha-Helical Rod protein 1, HCR) within the PSORS1 locus may contribute to the onset of psoriasis.
|
19551138 |
2009 |
Psoriasis
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
We aimed to determine whether the genetic polymorphisms of the HCR gene, SNPs n.7*A, and n.9*C were associated with an increased risk of psoriasis in Chinese patients.
|
15214895 |
2004 |
Psoriasis
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Presence of psoriatic arthritis was more pronounced in HCR- psoriasis (as well as in Cw6- psoriasis).
|
17340018 |
2007 |
Psoriasis
|
0.090 |
Biomarker
|
disease |
BEFREE |
The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene.
|
11348465 |
2001 |
Psoriasis
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
To understand better the function of HCR, we studied how HCR expression is altered in hyperproliferative skin diseases other than psoriasis and in cancers.
|
14675183 |
2003 |
Psoriasis
|
0.090 |
Biomarker
|
disease |
BEFREE |
Our results suggest a potential role for HCR in the pathogenesis of psoriasis.
|
10888604 |
2000 |
Antisocial Personality Disorder
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Logistic regression analyses identified unemployment, non-sexual violent index offense, higher risk scores (HCR-20), and Facet 1 (interpersonal deficits) of the Psychopathy Checklist-Revised (PCL-R) as significant predictors of treatment dropout.
|
30967799 |
2019 |
Antisocial Personality Disorder
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Violence risk ratings (measured by the Historical Clinical Risk Management-20 [HCR-20]) and psychopathy ratings (measured by the Psychopathy Checklist-Revised [PCL-R]) depended on the presence of a prior criminal record, such that those with a prior criminal record were perceived as a greater violence risk and as exhibiting more psychopathic traits than their clean-record counterparts.
|
31096835 |
2019 |