Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 Biomarker disease BEFREE This inverse relationship between miR-182 and ZIP1 also occurs in human prostate cancer tissue, which is known for Zn loss. 30397150 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 AlteredExpression disease BEFREE Recent studies reveal a strong association between prostate cancer progression and the downregulation of the zinc uptake transporters hZip1 and hZip3. 21940908 2011
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 AlteredExpression disease BEFREE RREB-1 overexpression results in down-regulation of hZIP1 and contributes to the loss of hZIP1 expression and zinc in prostate cancer. 21360563 2011
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 AlteredExpression disease BEFREE The Ras pathway and activation of RREB-1 are involved in hZIP1 down-regulation and may play a role in the decrease of the transporter expression in prostate cancer. 19802870 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 Biomarker disease BEFREE Our results show that hZIP1 overexpression has a functional effect on the malignant potential of prostate cancer cells via inhibition of NF-kappaB-dependent pathways and support the concept that hZIP1 may function as a tumor suppressor gene in prostate cancer. 18765529 2008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 AlteredExpression disease BEFREE To address this issue, the expression of hZIP1 and the depletion of zinc in malignant versus non-malignant prostate glands of prostate cancer tissue sections were analyzed. hZIP1 expression was also determined in malignant prostate cell lines. 16153295 2005
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.070 AlteredExpression disease BEFREE We have evaluated 58 prostate cancer tissues in 2 major racial groups (30 from whites and 28 from African Americans) for their ability to express 2 major human zinc transporters, hZIP1 and hZIP2. 12966353 2003