Asperger Syndrome
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
In a previous study, a Finnish group demonstrated that DISC1 polymorphisms were associated with autism and Asperger syndrome.
|
21569632 |
2011 |
Asperger Syndrome
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
The Disrupted in Schizophrenia 1 (DISC1) gene has been associated with the risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression, autism, and Asperger syndrome in different populations.
|
21222298 |
2011 |
Asperger Syndrome
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
The duplication contains seven genes including the DISC1 gene, an interesting candidate gene that has been associated to schizophrenia, bipolar disorder, autism and Asperger syndrome.
|
20002455 |
2010 |
Asperger Syndrome
|
0.360 |
Biomarker
|
disease |
BEFREE |
Disrupted in Schizophrenia 1 (DISC1) is currently one of the most interesting candidate genes for major mental illness, having been demonstrated to associate with schizophrenia, bipolar disorder, major depression, autism, and Asperger's syndrome.
|
19251251 |
2009 |
Asperger Syndrome
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
Disrupted in schizophrenia 1 (DISC1) has been associated with risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression, autism and Asperger syndrome, but apart from in the original translocation family, true causal variants have yet to be confirmed.
|
18317464 |
2009 |
Asperger Syndrome
|
0.360 |
Biomarker
|
disease |
LHGDN |
In addition, evidence for association to Asperger syndrome was observed with an intragenic single nucleotide polymorphism (SNP) of DISC1 (rs1322784; P=0.0058), as well as with a three-SNP haplotype (P=0.0013) overlapping the HEP3 haplotype, that was previously observed to associate with schizophrenia in Finnish families.
|
17579608 |
2008 |
Asperger Syndrome
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
Here we have addressed the allelic diversity of the DISC1, DISC2 and TRAX genes, clustered in 1q42, in Finnish families ascertained for infantile autism (97 families, n(affected)=138) and Asperger syndrome (29 families, n(affected)=143).
|
17579608 |
2008 |
Asperger Syndrome
|
0.360 |
Biomarker
|
disease |
CTD_human |
In addition, evidence for association to Asperger syndrome was observed with an intragenic single nucleotide polymorphism (SNP) of DISC1 (rs1322784; P=0.0058), as well as with a three-SNP haplotype (P=0.0013) overlapping the HEP3 haplotype, that was previously observed to associate with schizophrenia in Finnish families.
|
17579608 |
2008 |