EML4, EMAP like 4, 27436

N. diseases: 100; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.040 Biomarker group BEFREE About 4% of non-small-cell lung carcinomas involve an EML4-ALK tyrosine kinase fusion gene and occur almost absolutely in carcinomas arising in non-smokers. 27606884 2018
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.040 Biomarker group BEFREE This case suggests that echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion is an oncogenic event in not only carcinomas but also sarcomas originating from stromal cells. 24277751 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.040 GeneticVariation group BEFREE EML4-ALK translocation is associated with early-onset and less-differentiated carcinomas. 25407901 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.040 AlteredExpression group BEFREE Five of 149 adenocarcinomas (3.4%) showed EML4-ALK fusion mRNA, this being totally lacking in carcinomas of other types (0/72). 18166835 2008