GNAS, GNAS complex locus, 2778

N. diseases: 536; N. variants: 61
Disease: Multinodular goiter ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0342208
Disease: Multinodular goiter
Multinodular goiter 		0.010 GeneticVariation disease BEFREE The aim of the study was to investigate whether the mutations of the GNAS gene and thyroid-stimulating hormone receptor (TSHR) gene were a potential molecular biological mechanism for subclinical toxic multinodular goiter (sTMG) and to evaluate the association of these mutations with the clinicopathological features of these disorders.Forty-four patients with sTMG and 20 controls(multinodular goiter) from Heilongjiang province of China who underwent subtotal thyroidectomy were recruited. 19826830 2010