GNB3, G protein subunit beta 3, 2784

N. diseases: 192; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE The GNB3 TT genotype is a risk factor for CAD independent of other established cardiovascular risk factors in Chinese hypertensive patients. 28067546 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE Moreover, genotypes of the GNB3 polymorphism have been associated with development of coronary artery disease, and the 825T allele is thought to influence the process of atherosclerosis. 25463071 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE This truncated protein carried by GNB3 T allele carriers is linked to coronary artery disease and implicated as a genetic marker of drug response. 20096003 2010
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease LHGDN Thus, in the Russian population coronary artery disease is associated with GNB3 allele C and genotype CC. 17958314 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE We conclude that a major contribution of GNB3 gene variants to CAD or MI risk is unlikely. 16908025 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 Biomarker disease CTD_human C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population. 16141801 2005
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE We tested whether GNB3 C825T is associated with an increased risk of coronary artery disease (CAD). 12618278 2003
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease LHGDN We tested whether GNB3 C825T is associated with an increased risk of coronary artery disease (CAD). 12618278 2003
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE Genotyping at the ACE and GNB3 loci was performed on 585 patients with coronary artery disease with (n=270) or without (n=315) previous MI. 11116112 2000
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.380 GeneticVariation disease BEFREE C825T polymorphism in the G protein beta3 subunit gene (GNB3) has been associated with arterial hypertension, coronary artery disease and myocardial infarction. 10704626 2000