Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE Association of ABO blood groups with the severity of coronary artery disease: a cross-sectional study. 31645856 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study. 31092877 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE The ABO locus is associated with increased platelet aggregation in patients with stable coronary artery disease. 30837090 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE Type non-O of the ABO blood group system has been associated with coronary artery disease, thrombosis, and a worse prognosis. 29958715 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 AlteredExpression disease BEFREE While exposing the polygenic architecture of circulating lipids and the underpinnings of dyslipidaemia, these genome-wide association studies (GWAS) have provided further evidence of the critical role that lipids play in coronary heart disease (CHD) risk, as indicated by the 2.7-fold enrichment for macrophage gene expression in atherosclerotic plaques and the association of 25 loci (such as PCSK9, APOB, ABCG5-G8, KCNK5, LPL, HMGCR, NPC1L1, CETP, TRIB1, ABO, PMAIP1-MC4R, and LDLR) with CHD. 29800275 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE ABO blood groups have been confirmed to be associated with cardiovascular diseases such as coronary artery disease. 27988281 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE The present study demonstrates that blood type O was independently and positively associated with an open culprit artery in patients with AMI, suggesting that the ABO blood type is not only associated with the susceptibility to coronary artery disease but also to spontaneous reperfusion in AMI patients. 28387531 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE ABO blood group may have a role for CHD, and this novel finding provides ABO blood group as a possible marker for CHD, but more studies need to be done. 28211529 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE ABO blood group is a risk factor for coronary artery disease in patients with poor blood pressure control. 28513229 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE The genotype distribution, allele frequencies and haplotypes of the eNOS -786T/C, 4b/4a and 894G/T were significantly different between CHD patients, FDRS and controls. eNOS gene haplotypes GCB, TCB (G-allele of 894G/T, C-allele -786T/C, B-allele of Intron 4b/4a respectively) were associated with high nitrite/nitrate levels compared to GTB in both FDRS and CHD patients (p < 0.01). 27613099 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE Risk loci for ischemic stroke and its subtypes have been implicated in atrial fibrillation (PITX2 and ZFHX3), coronary artery disease (ABO, chr9p21, HDAC9, and ALDH2), blood pressure (ALDH2 and HDAC9), pericyte and smooth muscle cell development (FOXF2), coagulation (HABP2), carotid plaque formation (MMP12), and neuro-inflammation (TSPAN2). 27796860 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE It appears that only the ABO locus is a shared risk factor for coronary artery disease and VTE. 24745723 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE Since distinct genome-wide association studies linked the ABO gene with myocardial infarction (MI) in the presence of coronary atherosclerosis and with coronary artery disease, these findings may not only enhance our understanding of adhesion molecule biology, but may also provide a focus for several novel research avenues. 23300549 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease GWASCAT Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. 21239051 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease GWASDB Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. 21239051 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 GeneticVariation disease BEFREE ABO blood group alleles: A risk factor for coronary artery disease. An angiographic study. 20371059 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.200 Biomarker disease BEFREE ABO blood groups and coronary heart disease (CHD). A study in subjects with severe and latent CHD. 7455973 1980