ANGPT1, angiopoietin 1, 284

N. diseases: 340; N. variants: 18
Disease: Pulmonary Hypertension ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.210 Biomarker phenotype RGD Since both Ang-1/Tie2 and VEGF promote angiogenesis and vascular survival, and play protective roles in the adaptation of microvascular changes during the onset of PH, the downregulation of both Ang-1/Tie2 and VEGF and upregulation of Ang-3 appear to be associated with vascular rarefaction and the development of hypoxic PH. 18073453 2008
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.210 Biomarker phenotype LHGDN Angiopoietin/Tie2 pathway influences smooth muscle hyperplasia in idiopathic pulmonary hypertension. 16917117 2006