GRB2, growth factor receptor bound protein 2, 2885

N. diseases: 122; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE We used two publicly available leukemia data sources: ALL-IDB and ASH Image Bank. 31450720 2019
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE We hypothesised that inhibition of Grb2 would suppress ERK1 and ERK2 activation and inhibit leukaemia progression. 29550383 2018
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE Our data, together with other investigators' data, strongly indicate that Grb2 and Crkl are vital for the maintenance of cell growth in Ph+ leukemias. 9199202 1997
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE Tyrosine phosphorylation of the proto-oncogene product Vav and its association with the adapter Grb2/Ash in a human leukemia cell line UT-7. 7539782 1995