GRB2, growth factor receptor bound protein 2, 2885

N. diseases: 122; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 Biomarker disease BEFREE Keeping in view the limited toxicity of Withania somnifera (Ashwagandha), the current study was aimed to investigate the efficacy of Ashwagandha water extract (ASH-WEX) for anti-proliferative potential in neuroblastoma and its underlying signalling mechanisms. 23383150 2013
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 AlteredExpression disease BEFREE GAREM2 is expressed in some neuroblastoma cell lines and is also tyrosine-phosphorylated and bound to Grb2 after treatment with EGF. 24003223 2013
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 Biomarker disease BEFREE In the current study, we report that IGF-I induces a sustained tyrosine phosphorylation of Shc and its association with Grb2 in SH-SY5Y human neuroblastoma cells. 9852124 1998