GRN, granulin precursor, 2896

N. diseases: 412; N. variants: 66
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease BEFREE Our case report further corroborates the notion that, in addition to FTD, progranulin may be involved in the neurobiology of bipolar disorder type 1, and suggests to screen patients with late-onset bipolar disorder for GRN mutations. 28664756 2017
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease BEFREE Our study suggests that the potential of progranulin as a biomarker for bipolar disorder is genotype dependent. 28225367 2017
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 AlteredExpression disease BEFREE In addition, plasma progranulin levels are significantly decreased in BD [mean ± standard deviation (SD) 112 ± 35 versus 183 ± 93 ng/mL in controls; p < 0.001]. 24499389 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET In addition, plasma progranulin levels are significantly decreased in BD [mean ± standard deviation (SD) 112 ± 35 versus 183 ± 93 ng/mL in controls; p < 0.001]. 24499389 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Progranulin gene variability and plasma levels in bipolar disorder and schizophrenia. 22505994 2012
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 AlteredExpression disease BEFREE Progranulin gene variability and plasma levels in bipolar disorder and schizophrenia. 22505994 2012