KLF15, Kruppel like factor 15, 28999

N. diseases: 80; N. variants: 4
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 Biomarker disease BEFREE KLF15 may therefore be an effective therapeutic target for the treatment of heart failure and other cardiovascular diseases. 30831134 2019
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 AlteredExpression disease BEFREE Krüppel-like factor 15 (KLF15) has recently emerged as a critical transcriptional regulator of BCAA metabolism, and the absence of this transcription factor contributes to severe pathologies such as Duchenne muscular dystrophy and heart failure. 29288718 2018
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 GeneticVariation disease BEFREE It also discusses our recent paper that described the contribution of genetic variants in <i>KLF15</i> to the development of LVH and heart failure in high-risk patients. 29702551 2018
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 Biomarker disease BEFREE KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases. 28336438 2017
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 AlteredExpression disease BEFREE We show in human heart samples that KLF15 is induced after birth and reduced in heart failure, a myocardial expression pattern that parallels reliance on lipid oxidation. 24407292 2014
CUI: C0018801
Disease: Heart failure
Heart failure 		0.060 Biomarker disease BEFREE Mice deficient in Klf15 develop heart failure and aortic aneurysms in a p53-dependent and p300 acetyltransferase-dependent fashion. 20375365 2010