KLF15, Kruppel like factor 15, 28999

N. diseases: 80; N. variants: 4
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 Biomarker disease BEFREE KLF15 may therefore be an effective therapeutic target for the treatment of heart failure and other cardiovascular diseases. 30831134 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 GeneticVariation disease BEFREE It also discusses our recent paper that described the contribution of genetic variants in <i>KLF15</i> to the development of LVH and heart failure in high-risk patients. 29702551 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 AlteredExpression disease BEFREE Krüppel-like factor 15 (KLF15) has recently emerged as a critical transcriptional regulator of BCAA metabolism, and the absence of this transcription factor contributes to severe pathologies such as Duchenne muscular dystrophy and heart failure. 29288718 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 Biomarker disease BEFREE KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases. 28336438 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 AlteredExpression disease BEFREE We show in human heart samples that KLF15 is induced after birth and reduced in heart failure, a myocardial expression pattern that parallels reliance on lipid oxidation. 24407292 2014
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 Biomarker disease BEFREE Mice deficient in Klf15 develop heart failure and aortic aneurysms in a p53-dependent and p300 acetyltransferase-dependent fashion. 20375365 2010
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.070 AlteredExpression disease BEFREE The expression levels of KLF15 and GLUT4 were decreased at the left ventricular hypertrophy and congestive heart failure stage in a rat model. 19720047 2009