Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker disease BEFREE Disruption of the NMDA receptor GluN2A subunit abolishes inflammation-induced depression. 30296532 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 AlteredExpression disease BEFREE Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling pathway in rats. 29704590 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker disease PSYGENET These data suggest distinct roles of the GluN2A subunit as whole vs. its intracellular domain in modulating anxiety and depression-like symptoms and reveal differential molecular targets for the therapy of mood and anxiety disorders. 23557693 2013
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 PosttranslationalModification disease BEFREE Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. 19834457 2009
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker disease PSYGENET Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. 19834457 2009
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker disease PSYGENET NR2A at CA1 synapses is obligatory for the susceptibility of hippocampal plasticity to sleep loss. 19605640 2009
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.330 Biomarker disease PSYGENET Taken together, these data demonstrate a selective and robust reduction in anxiety- and depression-related behavior in NMDA receptor NR2A subunit KO mice. 16482087 2006