Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.140 PosttranslationalModification disease BEFREE <i>N</i>-methyl-D-aspartate receptor (NMDAR) subunit NR2B tyrosine phosphorylation mediated by Src family protein tyrosine kinases is closely associated with dyskinesia. 30350722 2019
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.140 Biomarker disease BEFREE These findings suggest that targeting NR2B/Src complexes can be one potential treatment for dyskinesia in Parkinson's disease. 30130562 2019
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.140 Biomarker disease BEFREE The objective of this study was to evaluate the effects of the NR2B selective N-methyl-D-aspartate receptor antagonist MK-0657 on levodopa-induced dyskinesias and motor symptoms in PD patients. 29059133 2018
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.140 Biomarker disease BEFREE Modulation of CaMKIIa-GluN2B interaction in levodopa-induced dyskinesia in 6-OHDA-lesioned Parkinson's rats. 30142538 2018
CUI: C0013384
Disease: Dyskinetic syndrome
Dyskinetic syndrome
0.140 Biomarker disease HPO