Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.050 Biomarker disease BEFREE Fifteen minutes after pilocarpine administration, animals received i.p. injections of saline solution (0.9% NaCl; SE + SAL group), ketamine (a non-selective and noncompetitive NMDAR antagonist; 25 mg/kg; SE + KET), CI-1041 (a GluN2B-containing NMDAR antagonist; 10 mg/kg; SE + CI group) or CP-101,606 (a NMDAR antagonist with great selectivity for NMDAR composed by GluN1/GluN2B diheteromers; 10 mg/kg; SE + CP group). 30639357 2019
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.050 AlteredExpression disease BEFREE However, AU had no significant effect on N-methyl-d-aspartate receptor subunit 2B (NR2B) expression in status epilepticus (SE). 30666488 2019
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.050 Biomarker disease BEFREE The present study aimed to investigate the mRNA expression of excitatory amino acid transporters 1-3 (EAATs) and the subunits of the NMDA (GluN1, GluN2a, and GluN2b) and AMPA (GluA1 and GluA2) glutamate receptors following status epilepticus in a rat lithium-pilocarpine model. 30189229 2018
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.050 AlteredExpression disease BEFREE Regulation of N-methyl-d-aspartate (NMDA) subunits NR2A and NR2B expression during status epilepticus (SE) remains incompletely understood. 27731509 2016
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus
0.050 Biomarker disease BEFREE Interestingly, blocking either NR2A- or NR2B-containing NMDARs decreased status epilepticus-induced neuronal cell death. 17234586 2007