GSK3B, glycogen synthase kinase 3 beta, 2932

N. diseases: 393; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 GeneticVariation disease BEFREE Brain Volume-Related Polymorphisms of the Glycogen Synthase Kinase-3β Gene and Their Effect on Antidepressant Treatment in Major Depressive Disorder. 31189175 2019
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 GeneticVariation disease BEFREE Notably, another promotor SNP (rs334558) of the GSK-3β gene is reportedly associated with unipolar depression, bipolar disorders, and dementia. 31742842 2019
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 Biomarker disease BEFREE Our results provide evidence that the GSK3B gene could be a promising region which contains genetic risk for both major depressive disorder and schizophrenia in the Han Chinese population. 26186530 2015
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 GeneticVariation disease BEFREE A haplotype of glycogen synthase kinase 3β is associated with early onset of unipolar major depression. 20618448 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 Biomarker disease CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 GeneticVariation disease BEFREE The combined effects of the BDNF and GSK3B genes modulate the relationship between negative life events and major depressive disorder. 20682308 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.360 Biomarker disease BEFREE Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population. 20033742 2010