GSR, glutathione-disulfide reductase, 2936

N. diseases: 206; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Biomarker disease CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Biomarker disease CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
CUI: C0242423
Disease: Ramsay Hunt Paralysis Syndrome
Ramsay Hunt Paralysis Syndrome 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752097
Disease: Autosomal Dominant Juvenile Parkinson Disease
Autosomal Dominant Juvenile Parkinson Disease 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752098
Disease: Autosomal Dominant Parkinsonism
Autosomal Dominant Parkinsonism 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752100
Disease: Autosomal Recessive Parkinsonism
Autosomal Recessive Parkinsonism 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752101
Disease: Parkinsonism, Experimental
Parkinsonism, Experimental 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752104
Disease: Familial Juvenile Parkinsonism
Familial Juvenile Parkinsonism 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0752105
Disease: Parkinsonism, Juvenile
Parkinsonism, Juvenile 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C1868675
Disease: PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE
PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE 		0.300 Therapeutic disease CTD_human Protective role of glutathione reductase in paraquat induced neurotoxicity. 22721943 2012
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker disease CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
CUI: C0013604
Disease: Edema
Edema 		0.300 Biomarker phenotype CTD_human Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. 19874808 2010
CUI: C0020615
Disease: Hypoglycemia
Hypoglycemia 		0.300 Biomarker disease CTD_human Both STZ-induced diabetes and insulin-induced hypoglycemia promote a significant increase in TBARS levels and a decrease in glutathione disulfide reductase activity. 20620209 2010
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker disease CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
CUI: C0151603
Disease: Anasarca
Anasarca 		0.300 Biomarker phenotype CTD_human Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. 19874808 2010
CUI: C0271708
Disease: Fasting Hypoglycemia
Fasting Hypoglycemia 		0.300 Biomarker phenotype CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
CUI: C0271710
Disease: Reactive hypoglycemia
Reactive hypoglycemia 		0.300 Biomarker disease CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
CUI: C3714618
Disease: Primary Hyperthyroidism
Primary Hyperthyroidism 		0.300 Biomarker disease CTD_human Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin. 19914224 2010
CUI: C0393554
Disease: Amyotrophic Lateral Sclerosis With Dementia
Amyotrophic Lateral Sclerosis With Dementia 		0.300 Biomarker disease CTD_human Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. 16681429 2006
CUI: C0543859
Disease: Amyotrophic Lateral Sclerosis, Guam Form
Amyotrophic Lateral Sclerosis, Guam Form 		0.300 Biomarker disease CTD_human Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. 16681429 2006
CUI: C0033626
Disease: Protein Deficiency
Protein Deficiency 		0.300 Biomarker disease CTD_human Protein deficiency in normal rats resulted in a significant increase in hepatic activities of catalase, glutathione peroxidase, glutathione reductase, and glutathione-S-transferase and the levels of lipid peroxidation. 15865262 2005
CUI: C0270715
Disease: Degenerative Diseases, Central Nervous System
Degenerative Diseases, Central Nervous System 		0.300 Biomarker group CTD_human Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy. 15964507 2005
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders 		0.300 Biomarker group CTD_human Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy. 15964507 2005
CUI: C0751733
Disease: Degenerative Diseases, Spinal Cord
Degenerative Diseases, Spinal Cord 		0.300 Biomarker group CTD_human Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy. 15964507 2005
CUI: C0520572
Disease: Enzymopathy
Enzymopathy 		0.300 Biomarker group GENOMICS_ENGLAND Hereditary spherocytic anemia with deletion of the short arm of chromosome 8. 8533822 1995