GSTM1, glutathione S-transferase mu 1, 2944

N. diseases: 627; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 Biomarker group BEFREE Transcriptomic profiling using paired colorectal tumor and adjacent normal mucosa tissues of XMEs (GSTM1,GSTA1,UGT1A8,UGT1A10,CYP3A4,CYP2C9,GSTP1,CYP2W1) by RNA microarray was compared using Wilcoxon rank-sum tests. 31740522 2020
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 Biomarker group CTD_human Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. 20878130 2010
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group LHGDN GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer. 18630481 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group LHGDN Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking. 18159984 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group LHGDN Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study. 12944179 2004
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group LHGDN Meat consumption, cigarette smoking, and genetic susceptibility in the etiology of colorectal cancer: results from a Dutch prospective study. 12074508 2002
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group BEFREE These results indicate that GSTM1 genotype may not necessarily reflect GST mu phenotype in colorectal tumors. 11809532 2002
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group LHGDN Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. 12072547 2002
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 GeneticVariation group BEFREE After grouping by tumor site, the GSTM1 null genotype was a risk factor among the subgroup with distal colorectal tumors (61.1%) (OR = 2.03; 95% CI, 1.06-3.90). 8824506 1996