GSTM1, glutathione S-transferase mu 1, 2944

N. diseases: 627; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 GeneticVariation disease BEFREE Patients with homozygous GSTM1 gene deletion reported higher anxiety (mean null genotype = 47.3 ± 9.2, non-null = 43.9 ± 7.8; P = .04), more depression (null = 51.0 ± 9.8, non-null = 47.0 ± 9.4; P = .03), and more global distress (null = 50.2 ± 9.7, non-null = 45.2 ± 9.9; P = .01). 22661588 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker disease PSYGENET Patients with homozygous GSTM1 gene deletion reported higher anxiety (mean null genotype = 47.3 ± 9.2, non-null = 43.9 ± 7.8; P = .04), more depression (null = 51.0 ± 9.8, non-null = 47.0 ± 9.4; P = .03), and more global distress (null = 50.2 ± 9.7, non-null = 45.2 ± 9.9; P = .01). 22661588 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 GeneticVariation disease BEFREE The GSTM1-missing (higher risk) group reported greater motivation to quit smoking, and both genetic testing groups reported lower depression than the control group at one-week follow-up (p < .05 for all). 18420756 2008
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker disease PSYGENET Association between genetic polymorphism of GSTT1 and depression score in individuals chronically exposed to natural sour gas. 18325667 2008
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker disease PSYGENET The GSTM1-missing (higher risk) group reported greater motivation to quit smoking, and both genetic testing groups reported lower depression than the control group at one-week follow-up (p < .05 for all). 18420756 2008
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.320 Biomarker disease PSYGENET Interictal behavioral disturbances: a search for molecular substrates. 1337448 1992