|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
To summarize, this meta-analysis indicates that Indians with the GSTT1 null-genotype has a raised hypertension risks; the GSTM1 null/GSTT1 null-genotype is association with raised hypertension risks, while the GSTM1 null-genotype is not associated with hypertension risks.
|
30420646 |
2019 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
No statistically significant association was observed between the GSTT1 null genotype and hypertension risk (OR = 1.14, 95% CI: 0.85, 1.53; P = 0.000, I2 = 80.3%).
|
25742618 |
2015 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
It is concluded that ACE (rs 4646994), FABP2 (rs1799883) and GST (GSTM1 null or positive genotype and GSTT1 null or positive genotype) genes polymorphism are associated with HTN.
|
25357227 |
2015 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Absence of both GSTM1 and GSTT1 genes was significantly associated with pulmonary hypertension (P = 0.04).
|
25880856 |
2015 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We aimed to investigate effects of long-term traffic-related air pollution exposure, as well as variants in GSTP1, GSTT1 and GSTCD, on risk of acute myocardial infarction (AMI) and hypertension.
|
24915237 |
2014 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Meta-analysis revealed significant associations between the null genotypes of GSTM1 (OR: 1.22; 95% CI: 1.08-1.39; p=0.002) and GSTT1 (OR: 1.30; 95% CI: 1.13-1.50; p=0.0003) and risk of hypertension.
|
24788870 |
2014 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
GSTM1-null and GSTT1-null genotypes are associated with essential arterial hypertension in patients with type 2 diabetes.
|
24685594 |
2014 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
CTD_human |
A custom rat and baboon hypertension gene array to compare experimental models.
|
22228705 |
2012 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
After adjustment for age, sex, smoking, BMI, lipid parameters and duration of hypertension and diabetes carriers of GSTT1-0 genotype showed an increased risk for higher plaque score (OR=2.29; p=0.012), but no association with CIMT and plaque stability was observed.
|
22330623 |
2012 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
This study analyzed all GST gene that, in other research, have been studied in relation to arterial hypertension and the GSTO polymorphisms, showing an association only with GSTT1.
|
21656129 |
2011 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Tobacco users with the GSTT1 null genotype were at an increased risk for hypertension.
|
21728793 |
2011 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
In the current study, allelic polymorphisms of GSTM1 and GSTT1 were analyzed in three ethnic groups of North East (NE) India where a high prevalence of various cancers and other diseases such as hypertension, tuberculosis, and asthma have been reported.
|
20073549 |
2010 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We investigated a possible association between hypertension and haptoglobin, angiotensin I-converting enzyme (ACE), glutathione S-transferases GSTM1 and GSTT1, MnSOD (Val9Ala), CAT (-21A/T), and GPX1 (Pro198Leu) gene polymorphisms in an urban Brazilian population group from Brasília.
|
21053180 |
2010 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).
|
18840420 |
2009 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
LHGDN |
The risk of hypertension was significantly increased in the GSTA1*B allele carriers having also the GSTM1 null genotype or both the GSTM1 and GSTT1 null genotypes (adjusted OR: 2.4; 95% CI: 1.2-4.9; adjusted OR: 3.1; 95% CI: 1.0-9.5, respectively).
|
18300949 |
2008 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The risk of hypertension was significantly increased in the GSTA1*B allele carriers having also the GSTM1 null genotype or both the GSTM1 and GSTT1 null genotypes (adjusted OR: 2.4; 95% CI: 1.2-4.9; adjusted OR: 3.1; 95% CI: 1.0-9.5, respectively).
|
18300949 |
2008 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Deletion of GSTT1 gene might be considered as protective factor for hypertension.
|
17182005 |
2007 |
|
Hypertensive disease
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Deletion of GSTT1 gene might be considered as protective factor for hypertension.
|
17182005 |
2007 |
|
Hypertensive disease
|
0.400 |
Biomarker
|
group |
BEFREE |
The data show that while M1 and T1 null genotypes were not significantly increased in SSc compared to ethnically matched controls, their frequencies (especially T1 nulls) were significantly higher among SSc patients with hypertension and pulmonary involvement.
|
11477481 |
2001 |