|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
The GSTM1 present genotype was significantly associated with decreased risks of ATDILI (risk ratio(RR): 0.81, 95% confidence interval (CI): 0.75-0.88, P < 0.0001) and SCZ (RR: 0.88, 95%CI: 0.80-0.96, P = 0.004) according to the fixed-effect model, while the GSTT1 present genotype was significantly associated only with a high risk of SCZ (RR: 1.17, 95%CI: 1.04-1.32, P = 0.01) according to both the random- and fixed-effect models, but not with ATDILI (P = 0.82) according to the fixed-effect model.
|
26046920 |
2015 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we confirmed associations between schizophrenia and the common CNVs in the glutathione (GSH)-related genes GSTT1, DDTL, and GSTM1 using quantitative real-time polymerase chain reaction analyses of 620 patients with schizophrenia and in 622 controls.
|
26175060 |
2015 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
Our meta-analysis results revealed that GSTM1, GSTT1, and GSTP1 polymorphisms were not related to risk of schizophrenia (p > 0.05 in each model).
|
26295386 |
2015 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
The aim of this case-control study was to investigate the association of the promoter hypermethylation status of glutathione S-transferase T1 (GSTT1) and glutathione S-transferase P1 (GSTP1) genes with the risk of schizophrenia.
|
25358668 |
2014 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
The aim of this case-control study was to investigate the association of the promoter hypermethylation status of glutathione S-transferase T1 (GSTT1) and glutathione S-transferase P1 (GSTP1) genes with the risk of schizophrenia.
|
25358668 |
2014 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, the combination of the GSTM1 and GSTT1 null genotypes showed a non-significant trend to an increased risk of schizophrenia.
|
23107768 |
2013 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
Furthermore, the combination of the GSTM1 and GSTT1 null genotypes showed a non-significant trend to an increased risk of schizophrenia.
|
23107768 |
2013 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
Genetic polymorphisms of glutathione S-transferases GSTM1, GSTT1, GSTP1 and GSTA1 as risk factors for schizophrenia.
|
21093063 |
2011 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
We isolated genomic DNA from peripheral blood of 93 individuals with SCZ and 99 healthy control subjects' genotypes analyzing them for GSTM1, GSTT1 and GSTP1 using polymerase chain reaction.
|
22874804 |
2011 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
We found that the combination of the absence of GSTM1 gene with the of the GSTM1 gene with the polymorphism GSTA1*B/*B, and the presence of the GSTT1 gene, represents a risk factor for schizophrenia, indicating that the combination of different GST polymorphisms has a role in the predisposition to schizophrenia, probably affecting the capacity of the cell to detoxify the oxidized metabolites of catecholamines.
|
21093063 |
2011 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
In order to find the possible influence of polymorphism of GSTT1 (a member of class theta glutathione S-transferase) on rate-corrected QT interval (QTc) of schizophrenia patients, the present study was done.
|
19148781 |
2009 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
In order to find the possible influence of polymorphism of GSTT1 (a member of class theta glutathione S-transferase) on rate-corrected QT interval (QTc) of schizophrenia patients, the present study was done.
|
19148781 |
2009 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
On the other word, the positive GSTT1 genotype significantly increased the risk of schizophrenia.
|
17586054 |
2007 |