|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
In the analysis by histological type, GSTT1 null genotype was correlated with a significantly increased risk of esophageal squamous cell carcinoma (OR = 1.34; 95% CI 1.12-1.61; <i>P</i> < 0.05), particularly among Asians (OR = 1.54; 95% CI 1.30-1.82; <i>P</i> < 0.05), but not among Caucasians or Africans (OR = 0.87; 95% CI 0.48-1.57; <i>P</i> > 0.05 for Caucasians and OR = 1.32; 95% CI 0.98-1.77; <i>P</i> > 0.05 for Africans).
|
29599931 |
2018 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
This study indicates that GSTT1 null genotype is associated with ESCC risk in Kashmiri population.
|
25432134 |
2015 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Low or intermediate activity enzyme genotypes for GSTM1, GSTA1, GSTP1 I105V and A114V as well as for GSTT1, did not significantly modify the risk for ESCC or EAC in our Dutch population.
|
23731957 |
2013 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
Biomarker
|
disease |
BEFREE |
MDR analysis revealed two predictor models for ESCC with promoter hypermethylation (Tobacco chewing/Smoking/Betel quid chewing/GSTT1 null) and ESCC without promoter hypermethylation (Betel quid chewing/Alcohol/GSTT1) with TBA of 0.69 and 0.75 respectively and CVC of 10/10 in both models.
|
23596512 |
2013 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Neither the GSTT1 deletion nor the GSTP1 Ile105Val polymorphism was associated with OSCC risk in the Black or Mixed Ancestry populations.
|
22216261 |
2011 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
The homozygous GSTT1*0 genotype was associated with increased risk of OSCC (OR = 1.71, 95%CI 1.18-2.46) while the homozygous GSTM1*0 genotype was associated with significantly decreased risk of OSCC in the Mixed Ancestry subjects (OR= 0.39, 95%CI 0.25-0.62).
|
20540773 |
2010 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Therefore, in this study, we analyzed the risk of ESCC associated with tobacco and alcohol consumption and with polymorphisms of CYP2A6 (CYP2A6*2), CYP2E1 (CYP2E1*5B, CYP2E1*6), GSTP1 (Ile105Val), GSTM1 and GSTT1 null genotypes in 126 cases and 252 age- and gender-matched controls.
|
17916905 |
2007 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Our results demonstrated that dietary and environmental exposures, some demographic parameters and genetic polymorphism of GSTT1 may play important roles in the development of ESCC in Huaian area, China.
|
17173682 |
2006 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
Biomarker
|
disease |
CTD_human |
Our results demonstrated that dietary and environmental exposures, some demographic parameters and genetic polymorphism of GSTT1 may play important roles in the development of ESCC in Huaian area, China.
|
17173682 |
2006 |
|
Squamous cell carcinoma of esophagus
|
0.390 |
Biomarker
|
disease |
BEFREE |
To determine if genetic polymorphisms of CYP1A1, GSTM1, GSTP1, or GSTT1 are associated with an increased risk of developing esophageal squamous cell carcinoma (ESCC), gastric cardia cancer (GCC), or either in a high-risk Asian population.
|
15801491 |
2004 |