|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Consequences of universal MSI/IHC in screening ENDOMETRIAL cancer patients for Lynch syndrome.
|
24933100 |
2014 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Multigene Panel Testing Provides a New Perspective on Lynch Syndrome.
|
28514183 |
2017 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Prospective evaluation of molecular screening for Lynch syndrome in patients with endometrial cancer ≤ 70 years.
|
22306203 |
2012 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
|
24763289 |
2014 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families.
|
23729658 |
2013 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
[Constitutional mismatch repair deficiency syndrome].
|
26200421 |
2015 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Frequency of constitutional MSH6 mutations in a consecutive series of families with clinical suspicion of HNPCC.
|
17718861 |
2007 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing.
|
25559809 |
2015 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Feasibility of screening for Lynch syndrome among patients with colorectal cancer.
|
18809606 |
2008 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
LHGDN |
A new interphase fluorescence in situ hybridization approach for genomic rearrangements involving MLH1 and MSH6 in hereditary nonpolyposis colorectal cancer-suspected mutation-negative patients.
|
17498565 |
2007 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein.
|
23621914 |
2013 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
LOVD v.2.0: the next generation in gene variant databases.
|
21520333 |
2011 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
|
24362816 |
2014 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
|
22949379 |
2013 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Characterization of two Ashkenazi Jewish founder mutations in MSH6 gene causing Lynch syndrome.
|
21155762 |
2011 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
|
27978560 |
2017 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.
|
28944238 |
2017 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts.
|
18269114 |
2008 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
|
19851887 |
2010 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
LHGDN |
A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.
|
18625694 |
2008 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity.
|
28531214 |
2017 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
CLINVAR |
Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers.
|
20587412 |
2010 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
LHGDN |
Six novel heterozygous MLH1, MSH2, and MSH6 and one homozygous MLH1 germline mutations in hereditary nonpolyposis colorectal cancer.
|
15571801 |
2004 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
GeneticVariation
|
group |
LHGDN |
Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome.
|
17653898 |
2007 |