USP25, ubiquitin specific peptidase 25, 29761

N. diseases: 21; N. variants: 1
Disease: Down Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.020 Biomarker disease BEFREE An increase in USP25 gene dosage in Down syndrome patients could seriously disturb the balance between ubiquitinated and deubiquitinated substrates. 10644437 1999
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.020 AlteredExpression disease BEFREE Concerning function, USP25 overexpression in Down syndrome fetal brains was shown by real-time PCR. 11597335 2001