SENP1, SUMO specific peptidase 1, 29843

N. diseases: 79; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.020 Biomarker disease BEFREE Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression. 20079608 2010
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.020 AlteredExpression disease BEFREE Our findings indicate that in RA SFs overexpression of SENP1 can alter the SUMO-1-mediated recruitment of DAXX to PML NBs, thus influencing the proapoptotic effects of DAXX. 17360386 2007