SENP1, SUMO specific peptidase 1, 29843

N. diseases: 79; N. variants: 5
Disease: High-Grade Prostatic Intraepithelial Neoplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1168327
Disease: High-Grade Prostatic Intraepithelial Neoplasia
High-Grade Prostatic Intraepithelial Neoplasia 		0.020 GeneticVariation disease BEFREE However, mice expressing an androgen-responsive promoter driven SENP1-transgene (SENP1-Tg) develop high-grade prostatic intraepithelial neoplasia, but not carcinoma. 27852060 2017
CUI: C1168327
Disease: High-Grade Prostatic Intraepithelial Neoplasia
High-Grade Prostatic Intraepithelial Neoplasia 		0.020 AlteredExpression disease BEFREE Further pathological assessment of the mouse indicates that SENP1 overexpression induces transformation of the normal prostate gland and gradually facilitates the onset of high-grade prostatic intraepithelial neoplasia. 20551310 2010