H2AZ1, H2A.Z variant histone 1, 3015

N. diseases: 38; N. variants: 1
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression group BEFREE We assessed by immunohistochemistry tumor DNA methylation levels, the expression of methyltransferases DNMT3A, DNMT3B and DNMT3L as well as levels of histone modifications H3K9me2, H3K27me3, H3K4me1, H3K4me2/3, H3K9ac, and H2A.Z. 22819380 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 PosttranslationalModification group BEFREE Furthermore, deacetylation of H2A.Z at TSSs is increased with silencing of tumor suppressor genes. 21788347 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker group BEFREE Studying tumor suppressor genes (TSGs) silenced in cancer cell lines, we find that when active, these promoters are associated with H2A.Z but become enriched for macroH2A1 once silenced. 21030442 2011