H2AZ1, H2A.Z variant histone 1, 3015

N. diseases: 38; N. variants: 1
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker phenotype BEFREE H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma. 29532867 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker phenotype BEFREE Thus, our results provide important information for the molecular mechanisms of ZNF24 functions and suggest that ZNF24 may be is implicated in transcriptional regulation of genes associated with oncogenesis by interaction with H2A.Z. 22678762 2012
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 PosttranslationalModification phenotype BEFREE We show for the first time, that acetylation of H2A.Z is a key modification associated with gene activity in normal cells and epigenetic gene deregulation in tumorigenesis. 21788347 2012
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker phenotype BEFREE This article also presents the molecular pathways linking H2A.Z to breast cancer and mechanisms have been proposed to explain how altered H2A.Z leads to tumorigenesis. 20666725 2010