HDAC1, histone deacetylase 1, 3065

N. diseases: 277; N. variants: 1
Disease: Fetal Growth Retardation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.200 Biomarker phenotype RGD Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis. 24717552 2014
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.200 Biomarker phenotype RGD The fetal IUGR state was characterized by loss of USF-1 binding at the proximal promoter of Pdx1, recruitment of the histone deacetylase 1 (HDAC1) and the corepressor Sin3A, and deacetylation of histones H3 and H4. 18464933 2008
CUI: C0015934
Disease: Fetal Growth Retardation
Fetal Growth Retardation 		0.200 Biomarker phenotype RGD Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats. 16380407 2006