HFE, homeostatic iron regulator, 3077

N. diseases: 415; N. variants: 59
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011265
Disease: Presenile dementia
Presenile dementia
0.310 GeneticVariation disease BEFREE The results highlight apparently synergistic interactions between genetic and medical risk factors for dementia development, gender differences in risk factors, and involvement of HFE mutations. 24081379 2014
CUI: C0011265
Disease: Presenile dementia
Presenile dementia
0.310 Biomarker disease CTD_human Iron genes, iron load and risk of Alzheimer's disease. 17047092 2006
CUI: C0011265
Disease: Presenile dementia
Presenile dementia
0.310 Biomarker disease CTD_human Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease. 15060098 2004