HFE, homeostatic iron regulator, 3077

N. diseases: 415; N. variants: 59
Disease: Familial Alzheimer Disease (FAD) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 Biomarker disease CTD_human Iron genes, iron load and risk of Alzheimer's disease. 17047092 2006
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 Biomarker disease CTD_human Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease. 15060098 2004
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 GeneticVariation disease BEFREE Further, ApoE E4 effects in our FAD group are strongest in females lacking HFE mutations. 10861683 2000