HGF, hepatocyte growth factor, 3082

N. diseases: 671; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Biomarker disease BEFREE In co-culture, while ALF liver mesenchymal stromal cells (LMSCs) induced the expression of CXCR7, IDI and HGF in human umbilical cord endothelial cells (HUVECs), the ACLF LMSCs were defective and showed decreased production of SDF-1, HGF and MCSF compared to ALF. 31515741 2019
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Biomarker disease BEFREE Treatment with 4-PBA prevented the reduction of HGF in ALF rats. 28844859 2017
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 GeneticVariation disease BEFREE Transplantation of human hepatocytes cultured with deleted variant of hepatocyte growth factor prolongs the survival of mice with acute liver failure. 15912107 2005
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Therapeutic disease CTD_human A single administration of adenoviral-mediated HGF cDNA permits survival of mice from acute hepatic failure. 12479984 2003
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 AlteredExpression disease BEFREE Liver is unlikely to be the source of the high serum hepatocyte growth factor levels observed in acute liver failure. 11117560 2000
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Biomarker disease BEFREE Lack of its receptor (c-met) expression may explain a poor response of fulminant hepatic failure livers to exogenous hepatocyte growth factor that normally promotes liver growth and regeneration. 9286233 1997
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Biomarker disease BEFREE Mean values for serum HGF in acute hepatitis (AH), chronic hepatitis (CH), liver cirrhosis (LC), hepatocellular carcinoma (HCC), primary biliary cirrhosis (PBC), fulminant hepatic failure (FHF), and normal controls were 0.45, 0.40, 1.05, 1.06, 0.44, 16.40, and 0.27 ng/mL, respectively. 7806142 1995
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute
0.370 Biomarker disease BEFREE The purified HL-60 HGF was indistinguishable from human HGF in the plasma of patients with fulminant hepatic failure by studies of subunit constitution and amino acid composition. 1720310 1991