HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.510 Biomarker disease RGD Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia. 17101276 2007
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.510 Therapeutic disease RGD Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin. 18369388 2008
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.510 Biomarker disease CTD_human Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1alpha. 19429140 2009
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.510 AlteredExpression disease BEFREE We investigated the relationship between Ex-4 and HIF-1α by examining Ex-4-induced changes in HIF-1α expression in the gerbil hippocampus following global brain ischemia (in vivo) and in neuroblastoma cells (SH-SY5Y) and cortical primary neurons (in vitro). 24201448 2014