HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Disease: Superficial ulcer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333307
Disease: Superficial ulcer
Superficial ulcer 		0.030 AlteredExpression disease BEFREE Most cases were HIF1A positive (62%).No significant correlation was found between HIF1A expression and age, gender, tumor size, bone erosion, hemorrhage, or Ki-67 index. 30292665 2019
CUI: C0333307
Disease: Superficial ulcer
Superficial ulcer 		0.030 Biomarker disease BEFREE HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis. 31594926 2019
CUI: C0333307
Disease: Superficial ulcer
Superficial ulcer 		0.030 AlteredExpression disease BEFREE Interleukin 17 under hypoxia mimetic condition augments osteoclast mediated bone erosion and expression of HIF-1α and MMP-9. 30029761 2018