HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Disease: Non-Hereditary Clear Cell Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1334978
Disease: Non-Hereditary Clear Cell Renal Cell Carcinoma
Non-Hereditary Clear Cell Renal Cell Carcinoma 		0.030 Biomarker disease BEFREE Tuberous sclerosis complex protein 1 expression is affected by VHL Gene alterations and HIF-1α production in sporadic clear-cell renal cell carcinoma. 27845047 2016
CUI: C1334978
Disease: Non-Hereditary Clear Cell Renal Cell Carcinoma
Non-Hereditary Clear Cell Renal Cell Carcinoma 		0.030 GeneticVariation disease BEFREE In this study, we determined expression levels of EPO, and its correlation with VHL mutations and HIF-1α and HIF-2α expression in 82 patients identified with sCCRCC following nephrectomy. 21042786 2010
CUI: C1334978
Disease: Non-Hereditary Clear Cell Renal Cell Carcinoma
Non-Hereditary Clear Cell Renal Cell Carcinoma 		0.030 AlteredExpression disease BEFREE Inactivation of the VHL TSG in VHL tumours and in sporadic clear cell renal cell carcinoma (RCC) results in overexpression of HIF-1 and HIF-2. 15220362 2004