HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1510420
Disease: Cavitation
Cavitation
0.010 Biomarker disease BEFREE Human TB lesions are severely hypoxic and <i>M.tb</i> drives HIF-1α accumulation, synergistically increasing collagenase activity which will lead to lung destruction and cavitation. 27245780 2016