|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
A double amino-acid change in the HLA-A peptide-binding groove is associated with response to psychotropic treatment in patients with schizophrenia.
|
26218850 |
2015 |
|
Schizophrenia
|
0.470 |
AlteredExpression
|
disease |
BEFREE |
β2 microglobulin, HLA-A and Notch4 were all expressed in a pattern where inflammatory illness was associated with increased expression in controls but not in subjects with schizophrenia.
|
23395714 |
2013 |
|
Schizophrenia
|
0.470 |
Biomarker
|
disease |
PSYGENET |
β2 microglobulin, HLA-A and Notch4 were all expressed in a pattern where inflammatory illness was associated with increased expression in controls but not in subjects with schizophrenia.
|
23395714 |
2013 |
|
Schizophrenia
|
0.470 |
Biomarker
|
disease |
PSYGENET |
While searching for the "true" disease gene near the HLA-A gene, we discovered that homozygosity of the HLA-J M80469 pseudogene allele, in combination with HLA-A10 or HLA-A9, was associated with a high risk of schizophrenia (HLA-A10 relative risk = 29.33, p = 0.00019, patients N = 77, controls N = 214).
|
23083632 |
2013 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
While searching for the "true" disease gene near the HLA-A gene, we discovered that homozygosity of the HLA-J M80469 pseudogene allele, in combination with HLA-A10 or HLA-A9, was associated with a high risk of schizophrenia (HLA-A10 relative risk = 29.33, p = 0.00019, patients N = 77, controls N = 214).
|
23083632 |
2013 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
|
22688191 |
2012 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
However, no significant differences of these allelic frequencies were found between the patients and the control subjects, suggesting that the HLA-A gene was unlikely a major risk factor of schizophrenia in this sample.
|
18786593 |
2008 |
|
Schizophrenia
|
0.470 |
Biomarker
|
disease |
PSYGENET |
However, no significant differences of these allelic frequencies were found between the patients and the control subjects, suggesting that the HLA-A gene was unlikely a major risk factor of schizophrenia in this sample.
|
18786593 |
2008 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
Here, we report the results of a family-based candidate-gene study that brings together these two disparate lines of research by assessing maternal-fetal genotype matching at HLA-A, -B, and -DRB1 as a risk factor of schizophrenia.
|
16960807 |
2006 |
|
Schizophrenia
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
The present study investigated frequencies of HLA-A specificities in schizophrenia patients (ICD-10 and DSM-III-R, n=98) and sex-matched healthy controls (n=392) from population in the southwestern part of Japan.
|
11840504 |
2002 |
|
Schizophrenia
|
0.470 |
Biomarker
|
disease |
PSYGENET |
Thus, no evidence was obtained for an association between HLA-A and schizophrenia from the Japanese population.
|
12165412 |
2002 |
|
Schizophrenia
|
0.470 |
Biomarker
|
disease |
BEFREE |
Thus, no evidence was obtained for an association between HLA-A and schizophrenia from the Japanese population.
|
12165412 |
2002 |