|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Sixteen HLA-B alleles groups were associated with HIV-1 infection; seven of them (43.8%) were related to slow disease progression or reduced risk of MTCT, while six (37.5%) alleles groups were linked to a faster progression of HIV infection in children and to increased risk of MTCT.
|
30772367 |
2019 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
These data corroborate the existence of significant differences in HLA-B allele frequencies among the distinct AIDS progression profiles and further elucidate the role of HLA alleles in the outcome of HIV infections in diverse populations.
|
24718028 |
2014 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
In Zambia, ReA is associated with the HLA-B*57:03 allele, which is paradoxically also associated with slow progression of HIV infection.
|
24744085 |
2014 |
|
HIV Infections
|
0.500 |
Biomarker
|
group |
BEFREE |
HLA-B*5703 seems to be a protective allele against the progression of HIV infection but could influence the increased incidence of SpA observed in this population.
|
15641063 |
2005 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
The factors determining differential HIV disease outcome among individuals expressing protective HLA alleles such as HLA-B*27:05 and HLA-B*57:01 remain unknown.
|
29338738 |
2018 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
They specifically demonstrate that the influence of ZNRD1 alleles on disease progression rates are attributable to HLA-A10, help clarify the relationship between the HCP5, HLA-C and HLA-B*57 alleles, and reaffirm a critical role of HLA-B*57 alleles in HIV disease.
|
18982067 |
2008 |
|
HIV Infections
|
0.500 |
Biomarker
|
group |
BEFREE |
HIV subtype influences HLA-B*07:02-associated HIV disease outcome.
|
24010680 |
2014 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
BEFREE |
CCR5delta32 in the context of untreated HIV disease, or HLA-B*5701 allele on the abacavir hypersensitivity reaction in the context of HAART), it is more likely that HIV disease and treatment outcomes are influenced by a multitude of interacting genotypes and phenotypes, a hypothesis that will become increasingly possible to investigate as improvements in molecular and computational technologies are made.
|
16848275 |
2006 |
|
HIV Infections
|
0.500 |
Biomarker
|
group |
BEFREE |
Hence, aim of this study was to document association of HLA-B with HIV infection in DCs living in Mumbai, India.
|
24029662 |
2014 |
|
HIV Infections
|
0.500 |
Biomarker
|
group |
BEFREE |
In two HIV C clade-infected populations in South Africa and Zambia, we sought to elucidate the role of HLA-B*5703 in HIV disease outcome.
|
19307327 |
2009 |
|
HIV Infections
|
0.500 |
GeneticVariation
|
group |
LHGDN |
Influence of human leukocyte antigen-B22 alleles on the course of human immunodeficiency virus type 1 infection in 3 cohorts of white men.
|
12964117 |
2003 |
|
HIV Infections
|
0.500 |
AlteredExpression
|
group |
BEFREE |
A similar scenario is observed in humans where the expression of HLA-B*27 or HLA-B*57 has been linked to slow or no progression to AIDS after HIV infection.
|
26811146 |
2016 |