Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 GeneticVariation phenotype BEFREE CYP2C9*3 and HLA-B*51:01 allele carrier statuses are significantly associated with phenytoin-induced eruption; thus, checking this carrier status before prescription would decrease the incidence of phenytoin-induced eruption in clinical practice. 31646624 2019
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients. 29546073 2018
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE HLA-B*40:02 and DRB1*04:03 are risk factors for oxcarbazepine-induced maculopapular eruption. 27666425 2016
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 GeneticVariation phenotype BEFREE Among these allopurinol-induced cutaneous adverse drug reactions, HLA-B*58:01 was strongly associated with severe cutaneous adverse reactions (odds ratio [OR] = 44.0; 95% confidence interval = 21.5-90.3; P = 2.6 × 10(-41)), and the association was correlated with disease severity (OR = 44.0 for severe cutaneous adverse reactions, OR = 8.5 for maculopapular exanthema). 26996548 2016
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 GeneticVariation phenotype BEFREE Absence of HLA-B*1502 and HLA-A*3101 alleles in 9 Korean patients with antiepileptic drug-induced skin rash: a preliminary study. 25187890 2014
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE The association between oxcarbazepine-induced maculopapular eruption and HLA-B alleles in a northern Han Chinese population. 23829937 2013
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE Twelve patients with allopurinol-induced maculopapular exanthema were negative for HLA-B*5801, including one South-East Asian. 21790926 2012
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype CTD_human Genetic and ethnic risk factors associated with drug hypersensitivity. 20485159 2010
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE We describe the case of a 41-year-old Caucasian female patient, who tested HLA-B*5701 negative and developed fever and severe skin rash 10 weeks after the start of abacavir therapy. 19304978 2009
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 Biomarker phenotype BEFREE A strong association between the HLA-B*3505 and NVP-induced skin rash provides a novel insight into the pathogenesis of drug-induced rash in the HIV-infected population. 19104471 2009
CUI: C0015230
Disease: Exanthema
Exanthema
0.400 GeneticVariation phenotype BEFREE None of our patients (including two with blistering skin rashes) were positive for the HLA-B*1502 allele. 16981842 2006