Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE Subgroup analyses based on race system showed that HLA-DPB1⁎13:01 was significantly associated with an increased risk of cervical cancer in Asia (OR=1.834, 95%CI: 1.107-3.039, Pz=0.019). 30009173 2018
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE No association was detected between HLA-DPB1 alleles and cervical cancer risk in the Japanese population. 27193219 2016
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE We investigated whether polymorphisms in the HLA-DPB1 gene were associated with cervical cancer risk in a Taiwanese population. 26031576 2015
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE Our study provides the first systematic investigation of the association of genetic variants in the HLA-DP region with cervical cancer susceptibility and provides further insight into the contribution of polymorphisms in the HLA-DP region to risk of cervical cancer. 24743517 2014
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease GWASDB We additionally replicated an association between HLA-DPB1 and HLA-DPB2 (HLA-DPB1/2) at 6p21.32 and cervical cancer (rs4282438, Pcombined, stringently matched=4.52×10(-27), per-allele ORstringently matched=0.75). 23817570 2013
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE These findings indicate that HLA-DP rs3077 and rs9277535 were candidate susceptibility markers for cervical cancer in Chinese females. 23428460 2013
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker disease CTD_human We additionally replicated an association between HLA-DPB1 and HLA-DPB2 (HLA-DPB1/2) at 6p21.32 and cervical cancer (rs4282438, Pcombined, stringently matched=4.52×10(-27), per-allele ORstringently matched=0.75). 23817570 2013
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE The results illustrate the value of pathway-based analysis to mine genome-wide data, and point to the importance of the MHC region and specifically the HLA-DPB1 locus for susceptibility to cervical cancer. 21716314 2011
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE D6S2766 and D6S2764, which are located near to the region containing the HLA-DPB genes, were negatively related with cervical cancer (OR for the D6S2766-195 allele carriers = 0.50), and positively related with cervical cancer (OR for the D6S2764-209 allele carriers = 2.44), respectively. 18712835 2008
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker disease BEFREE These results indicate that HLA-DPB1*1301 may confer susceptibility to cervical cancer, and the haplotypes DRB1*150101-DQB1*0602 and DRB1*070101-DQB1*0201 may contribute to the resistance to the development of cervical cancer among Chinese women. 17349874 2007
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE Additionally, as for the HPV16 E6 prototype-positive cervical cancers, a significant positive association was found in DQB1*060101 allele (OR=5.95; P=0.002; Pc=0.036), and similar trends were observed for DQB1*030201 (OR=10.87, P<0.0001; Pc=0.0018), and DPB1*1301(OR=7.40, P=0.002; Pc=0.04). 17311339 2007
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation disease BEFREE The strongest class II effects are coming from the DQB1 and DRB1 loci, but the DPB1 locus also contributes to the susceptibility to cervical cancer. 15238505 2004