Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Protective associations between HLA-DRB1*13:02, HLA-DRB1*04:06, and HLA-DQB1*06:04 alleles and cervical cancer were found in the Korean population.
|
30352277 |
2019 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These findings supported that the HLA-DQB1 alleles may contribute to genetic susceptibility of cervical cancer.
|
26211583 |
2015 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
HLA-DQB1*0325 and HLA-DQB1*0332 probably act as cervical cancer susceptibility genes in Uyghur women from Xinjiang.
|
26681219 |
2015 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Persistent HPV16/18 infection in Indian women with the A-allele (rs6457617) of HLA-DQB1 and T-allele (rs16944) of IL-1β -511 is associated with development of cervical carcinoma.
|
25893807 |
2015 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2.
|
18650831 |
2008 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1 polymorphisms and risk for cervical cancer: a case-control study in a southern Chinese population.
|
17379283 |
2007 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HLA-DQB1*03 homozygosity (OR(age-adjusted) = 4.75; 95% CI: 1.17-19.30; P = 0.03) or p53Pro72Pro (OR(age-adjusted) = 5.84; 95% CI: 1.18-28.99; P = 0.03) was found to be significantly associated with CaCx, each in the absence of the other in this group but not when present jointly in contrast to those lacking both factors (P = 0.214).
|
17767549 |
2007 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This finding implies that polymorphic amino acids at the putative antigen binding residues 9 and 37 of HLA-DQB1 alleles may play an important role in the development of cervical cancer.
|
16425277 |
2006 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This is the first report of HLA-DQB1 alleles associated with cervical carcinoma in Venezuelan women.
|
15661220 |
2005 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Epidemiological studies have demonstrated an association between HLA-DQB1*03 alleles and the risk of cervical cancer induced by human papillomavirus (HPV).
|
15257408 |
2004 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, specific HLA-DQB1 sequences may be important in determining the immune response to HPV peptides and may affect the risk for cervical cancer after HPV infection in mestizo Honduran women.
|
10380373 |
1999 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recently, it was demonstrated that there is a high risk for cervical cancer and CIN in women with HLA DQB1 * 03 (RR = 7.1, p < 0.0009) (1).
|
8529095 |
1995 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between HLA-DQB1 alleles and risk for cervical cancer in African-American women.
|
8181853 |
1994 |