Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 AlteredExpression group BEFREE Further examination revealed that the level of HLA-DQB1 expression on tumor cells was positively correlated with CD4- and CD8-positive lymphocyte infiltration into the tumor. 31114327 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 GeneticVariation group BEFREE Patients with GC with HLA-DQB1*03 genotype had higher number of tumor size >6 cm, deeper depth of infiltration, higher LNM rate, and later stage of disease. 29667729 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE HLA-DQB1*03-positive PTC patients revealed an increased responsiveness of tumor epitopes in vitro. 27860539 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 AlteredExpression group BEFREE Future studies should focus on the clinical relevance of increased HLA-DQB1 protein expression facilitating tumor cell removal through increased immune surveillance. 24304973 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE The study suggests that HLA-DRB1*1501 and HLA-DQB1*0301 may influence the immune response to specific tumor and HPV-encoded epitopes and affect the risk of Kazakh ESCC in XinJiang, China. 22588649 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 GeneticVariation group BEFREE The HLA-DQB1*0301 allele, commonly associated to a high grade of cervical neoplasia and HPV infection, was present in homozygous in one mother and her child. 16920199 2006
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE In conclusion, HLA-DQB1(*)0602 confers susceptibility to gastric cancer, especially for male Taiwanese and proximal tumor location, while HLA-DQB1(*)0301 may have a protective effect on GC, probably through resistance to Helicobacter pylori infection. 11985790 2002
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE HLA-DQB1*0301 status, in addition to primary tumor thickness, was an independent prognostic indicator in these patients (Cox multivariate P = 0.02). 8756369 1996
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.090 Biomarker group BEFREE Association between HLA DQB1 * 03 and cervical intra-epithelial neoplasia. 8529095 1995