Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 GeneticVariation disease BEFREE Using the Autism Diagnostic Interview to assess clinical dimensions, higher scores on social (Pc = 0.006) and non-verbal functioning (Pc = 0.004) associated with the DRB1 *11 DQB1*07 haplotype. 29769579 2018
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 GeneticVariation disease BEFREE Acquisition of HLA-DRB1*011 and absence of HLA-DRB1*3 had significant risk for association with autism (odds ratio: 3.21 and 0.17, respectively; 95% CI: 1.65-6.31 and 0.06-0.45, respectively). 23110937 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 GeneticVariation disease BEFREE The results showed that the pattern of DRB1 allele frequencies was significantly different between patients with autism and the controls (P=0.047). 21716163 2012
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 GeneticVariation disease BEFREE These convergent findings from genetics and epidemiology imply that a subset of autism and schizophrenia cases may be underlain by genetically based neuroimmune alterations, and that analyses of the causes of risk and protective effects from DRB1 variants may provide new approaches to therapy. 21649858 2011
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease LHGDN The transmission disequilibrium test suggests that HLA-DR4 and DR13 are linked to autism spectrum disorder. 12039413 2002
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.350 Biomarker disease CTD_human Strong association of the third hypervariable region of HLA-DR beta 1 with autism. 8765331 1996