HLX, H2.0 like homeobox, 3142

N. diseases: 28; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis
0.030 Biomarker disease BEFREE As both HLX1 and HOXA9 are oncogenes implicated in leukemogenesis, we discuss the implications that the collaboration between Homeobox proteins and PRCs has for senescence and cancer. 24067365 2013
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis
0.030 AlteredExpression disease BEFREE These findings demonstrate that high levels of HB9 and HB24 expression are common features of acute leukemia and suggest the possibility that the dysregulated expression of these two genes may contribute to leukemogenesis. 7680402 1993
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis
0.030 AlteredExpression disease BEFREE Furthermore, dysregulated expression of HB24 impairs the normal differentiation of hematopoietic progenitors and may contribute to leukemogenesis. 1375114 1992